Matrix Effects in LC/MS

The three attached PDF files discuss our work in understanding and controlling matrix ionization effects in LC-MS/MS caused by endogenous phospholipids.  We employ a technique referred to as "in-source multiple reaction monitoring" (IS-MRM).

The first two files are in a poster format (Poster1 and Poster2) and the text file is a preprint version reflecting peer review and the editing process, but contains some content which was not peer reviewed.  The peer reviewed article was published in the J. Chro. B  (J. L. Little, M. F. Wempe, C. M. Buchanan, Journal of Chromatography B, 833 (2006) 219-230). 

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Poster1 (PDF file ASMS 2005)

Poster2 (PDF file ASMS 2006)

Text (PDF file Rough Draft of J Chro Article)

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